Stathmin1(phosphorylated Ser25)

Size

£518.00

SKU:: 335801
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Peptide corresponding to the sequence around phosphorylation site of serine 25 (I-L-S(p)-P-R) derived from human Stathmin 1.
Format:: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear Boehm M, et al. (2002) EMBO J 21(13): 3390-3401. Vadlamudi RK, et al. (2005) Mol Cell Biol 25(9): 3726-3736. Zilfou JT, et al. (2001) Mol Cell Biol 21(12): 3974-3985. Biernat J, et al. (2002) Mol Biol Cell 13(11): 4013-4028. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.