PBK (Cancer/Testis Antigen 84, CT84, Epididymis Luminal Protein 164, HEL164, Lymphokine Activated Killer T Cell Originated Protein Kinase, Lymphokine-activated Killer T-cell-originated Protein Kinase, MAPKK Like Protein Kinase, MAPKK-like Protein Kinase, Nori 3, Nori-3, Nori3, PDZ Binding Kinase, PDZ-binding Kinase, Serine/Threonine Protein Kinase, Spermatogenesis Related Protein Kinase, Spermatogenesis-related Protein Kinase, SPK, T LAK Cell Originated Protein Kinase, T-LAK Cell-originated Protein Kinase, TOPK)

Size

£394.00

SKU:: 327635
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant human Lymphokine-activated killer T-cell-originated protein kinase protein (aa1-322)
Format:: Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Extra Details:: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:200-1000 Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.