324096
MLC2 (phosphorylated Ser15)
Size
£518.00
- SKU:
- 324096
- Application:
- WB
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Peptide corresponding to the sequence around phosphorylation site of serine 15 (A-N-S(p)-N-V) derived from Human MLC2.
- Format:
- Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. 1) Xia, Y. et al. c-Jun downregulation by HDAC3-dependent transcriptionalrepression promotes osmotic stress-induced cell apoptosis. Mol. Cell 25,219–232 (2007). 2)Vander Heiden, M. G. et al. Evidence for an alternative glycolytic pathway inrapidly proliferating cells. Science 329, 1492–1499 (2010). 3) Fang, D. et al. Phosphorylation of beta-catenin by AKT promotes beta-catenintranscriptional activity. J. Biol. Chem. 282, 11221–11229 (2007). WB IF Recommended dilution: Western blotting:1:500~1:1000
- Shipping Conditions:
- Blue Ice