320583
INTS5 (Integrator Complex Subunit 5, Int5, KIAA1698)
Size
£800.00
- SKU:
- 320583
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Human INTS5
- Format:
- Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
- Extra Details:
- RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNAs (snRNA) U1 and U2 transcription, specifically in their 3’-box-dependent processing. A component of the integrator complex, INTS5 (integrator complex subunit 5), also known as KIAA1698, is a 1019aa multi-pass membrane protein localized to the nucleus. The gene encoding INTS5 maps to human chromosome 11q12.3 and mouse chromosome 19 A. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice