317597
GPC5 (Glypican-5)
Size
£364.00
- SKU:
- 317597
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to the Internal region of human GPC5.
- Format:
- Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- Glypican-5 is also known as GPC5 and is a 572aa protein. Glypican-5 is primarily expressed in adult brain tissue (where it is localized to neurons), but is also detected in fetal brain, lung and liver. Glypican-5 is a member of the glypican-related integral membrane proteoglycan family (GRIPS), which is characterized as having a core protein that is able to use glycosyl phosphatidylinositol to attach to the cytoplasmic membrane. Upregulation of glypican-5 has been found in active multiple sclerosis plaques, suggesting that glypican-5 may be involved in pathogenesis of multiple sclerosis. Upregulation of glypican-5 has also been recognized as having a strong correlation with lymphomas, as well as other tumors. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:40,000 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice