CNNM3 (Ancient Conserved Domain-containing Protein 3, ACDP3, Cyclin-M3)

Size

£460.00

SKU:: 311401
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Fusion protein of human CNNM3
Format:: Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Extra Details:: The ACDP3 gene, designated CNNM3 by the HUGO Nomenclature Committee, encodes a deduced 707aa protein. Northern blot analysis revealed ubiquitous expression of CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains, 2 CBS domains, a DUF21 domain, and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined, with highest expression in brain, kidney, liver, and heart. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:2000-1:5000 Immunohistochemistry: 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.