APLP2 (APPL2, Amyloid-like protein 2, APLP-2, APPH, Amyloid protein homolog, CDEI box-binding protein, CDEBP)

Size

£544.00

SKU:: 306373
Application:: WB
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthesized non-phosphopeptide derived from human APLP2 around the phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y).
Format:: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Extra Details:: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity.Sprecher C.A., Biochemistry 32:4481-4486(1993). Wasco W., Nat. Genet. 5:95-99(1993). von der Kammer H., DNA Cell Biol. 13:1137-1143(1994). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:3000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.