ANGPTL3

Size

£544.00

SKU:: 306039
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Fusion protein corresponding to C terminal 300 amino acids of Human Angiopoietin-related protein 3
Format:: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide, 50% glycerol.
Extra Details:: The protein encoded by this gene is a member of the Angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of Angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in Angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000-1:5000 Western Blot: 1:500-1:2000 Immunohistochemistry: 1:25-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.