CCL4 (MIP 1 beta, Secreted Protein G 26, ACT 2, ACT-2, ACT2, C C Motif Chemokine 4, C C Motif Chemokine 4 Like, CC Chemokine Ligand 4, CC Chemokine Ligand 4L1d2, CC Chemokine Ligand 4L2, Ccl4l 1, CCL4L, CCL4L1, Chemokine (C C Motif) Ligand 4, Chemokine (C C Motif) Ligand 4 Like 1, Chemokine (C C Motif) Ligand 4 Like 1, Telomeric, Chemokine (C C Motif) Ligand 4 Like 2, Chemokine CC Motif Ligand 4, G 26, G 26 T Lymphocyte Secreted Protein, G-26 T-lymphocyte-secreted Protein, HC21, LAG 1, LAG-1, LAG1, Lymphocyte Activation Gene 1, Lymphocyte Activation Gene 1 Protein, Macrophage Inflammatory Protein 1 beta, Macrophage Inflammatory Protein 1-beta, Macrophage Inflammatory Protein 1b2, MIP 1 beta, MIP-1-beta, MIP-1-beta(1-69), MIP-1-beta (3-69), MIP1 beta, MIP1B, MIP1B1, Monocyte Adherence Induced Protein 5 alpha, PAT 744, Protein H400, SCYA2, SCYA4, SCYA4L, Secreted Protein G 26, Secreted Protein G26, SIS gamma, SIS-gamma, Small Inducible Cytokine A4 (Homologous to Mouse Mip 1b),

Size

£620.00

SKU:: 303195
Application:: WB
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to rat CCL4 expressed in E. coli. (Position: A24-N92). Species sequence homology: human (80%) and mouse (86%)
Format:: Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile dH2O.
Extra Details:: Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice