ZRSR2 (U2 Small Nuclear Ribonucleoprotein Auxiliary Factor 35kD Subunit-Related Protein 2, CCCH Type Zinc Finger, RNA-Binding Motif and Serine/Arginine rich Protein 2, Renal Carcinoma antigen NY-REN-20, U2(RNU2) Small Nuclear RNA Auxiliary Factor 1-like 2, U2AF35-Related Protein, URP, ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP)

Size

£696.00

SKU:: 302883
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH conjugated synthetic peptide corresponding to aa453-482 at the C-terminal region of human ZRSR2.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing. Applications: Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry(Paraffin): 1:25 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.