MAFK (Transcription Factor MafK, Erythroid Transcription Factor NF-E2 p18 Subunit, MAFK)

Size

£696.00

SKU:: 302543
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: KLH conjugated synthetic peptide to human MAFK.
Clone:: 15k11
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Applications: Suitable for use in Indirect Flow Cytometry, Western Blot. Other applications not tested. Recommended Dilution: Indirect Flow Cytometry: 1:25 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.