KiSS-1 amide (Kisspeptin-10, Metastin amide) (Not for Export EU)

Size

£1,075.00

SKU:: 302028
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KiSS-1 (aa112-121), Metastin (aa45-54)
Format:: Supplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O.
Extra Details:: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq] Applications: Suitable for use in Indirect ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Indirect ELISA: 1:6400 Western Blot: 1:500-1000 Immunohistochemistry: 1:1000 Immunohistochemistry(ABC): 1:500-1000 Optimal dilutions to be determined by the researcher. Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice