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301901

Autotaxin (ATX) (Not for Export EU)

Size

£1,075.00

SKU:
301901
Purity:
Serum
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
aa754-783
Format:
Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
Extra Details:
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] Applications: Suitable for use in Indirect ELISA, Immunohistochemistry. Other applications not tested. Recommended Dilution: Indirect ELISA: 1:6400 Immunohistochemistry: 1:250-500 Optimal dilutions to be determined by the researcher. Sequence: pGlu-Tyr-Val-Glu-Gly-Ser-Ser-Ile-Pro-Val-Pro-Thr-His-Tyr-Tyr-Ser-Ile-Ile-Thr-Ser-Cys-Leu-Asp-Phe- Thr-Gln-Pro-Ala-Asp-Lys Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice