301811
HIV-1, CD4bd (gp120)
Size
£780.00
- SKU:
- 301811
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Human
- Immunogen:
- HIV-infected individuals by Epstein-Barr virus transformation of PMBCs followed by fusion with heteromyeloma cells. Epitope is discontinuous.
- Clone:
- 654-30D
- Format:
- Supplied as a lyophilized powder from PBS pH 7.4. No preservative added. Reconstitute with 100ul ddH2O.
- Extra Details:
- Of the two types of Human immunodeficiency virus (HIV) which have been characterized, HIV-1 is more infective and is prevalent globally. The HIV virion is encapsulated by a viral envelope that contains complexes of surface proteins including glycoprotein 120 (gp120), which are important for the virus to attach and fuse to infect target cells. The glycoprotein CD4 (cluster of differentiation 4), found on the surface of T-cells, interacts with gp120 and cytokine receptors to mediate the entry of the virus into cells. This antibody, has been shown to neutralize HIV-1. Applications: Suitable for use in Flow Cytometry, ELISA and Neutralization. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice