Substance P (Substance P, Tachykinin, Neuropeptide, Neurokinin, SP)

Size

£672.00

SKU:: 301768
Purity:: Supernatant
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Substance P
Clone:: NC1/34
Format:: Supplied as a lyophilized powder in 0.05% thimerosal. Reconstitute with 500ul ddH2O.
Extra Details:: The discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family; it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotions and antagonists of their receptors may be novel psychotropic drugs of the future. Applications: Suitable for use in Immunohistochemistry, Immunocytochemistry and ELISA. Other applications not tested. Recommended Dilutions: Immunohistochemistry (frozen): 1:100-1:200 Immunohistochemistry (paraffin): 1:100-1:200, does not require antigen retrieval prior to staining of formalin fixed, paraffin embedded sections. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice