301740
Rho-Guanine Nucleotide Exchange Factor (RGNEF)
Size
£664.00
- SKU:
- 301740
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Peptide corresponding to the RNA binding domain of RNEGF
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4. No preservative added. Reconstitute with 100ul ddH2O.
- Extra Details:
- The human Rho guanine nucleotide exchange factor (RGNEF) is a homolog of mouse p190RhoGEF that has been recently identified a novel human NFL mRNA binding protein in Amyotrophic Lateral Sclerosis (ALS) affected spinal cords. ALS-also known as Charcot's Disease, Lou Gehrig's disease and Motor Neuron Disease - is a rapidly progressive, and fatal, neuromuscular disease characterized by the gradual degeneration and death of motor neurons in the brain and spinal cord, which lead to progressive paralysis of the muscles. Applications: Suitable for use in Immunofluorescence, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunofluorescence: 1:100 Immunohistochemistry: 1:100-1:500 Immunoprecipitation: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice