Hemojuvelin (Not for Export EU)

Size

£544.00

SKU:: 301662
Application:: WB
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Full length protein corresponding to mouse hemojuvelin.
Format:: Supplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O.
Extra Details:: Hemojuvelin (HJV) belongs to the repulsive guidance molecule (RGM) family. HJV is highly expressed in the liver, skeletal muscle and heart and seems to play a role in iron absorption and release from cells. Defects in HJV are responsible for the iron overload condition known as juvenile hemochromatosis in humans. HJV is a co-receptor for bone morphogenetic protein (BMP) signaling that regulates hepcidin expression and iron metabolism. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.