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301653

GluR3B (Glutamate Receptor 3B, Glur3)

Size

£672.00

SKU:
301653
Purity:
Purified by Protein G affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Synthetic peptide corresponding to of aa372-391 of mouse GluR3 (NEYERFVPFSDQQISNDSAS).
Clone:
Glu149.29.61
Format:
Supplied as a lyophilized powder from PBS pH 7.4. Reconstitute with 100ul sterile ddH2O.
Extra Details:
Glutamate is the main excitatory neurotransmitter in the mammalian central nervous system (CNS). Its receptors are either metabotropic or ionotropic. The alpha-aa-3-hydroxy-5- methyl- 4-isoxazolepropionic acid receptor, also known as the AMPA receptor, is an ionotropic receptor made up of homomeric or heteromeric arrangments of Glutamate Receptor (GluR) subunits 1 to 4. GluR3 is one of the most common AMPA receptor in the CNS. The receptors are localized mainly post-synaptically and play important roles in the development and function of the nervous system. Autoimmunity to glutamate receptors may contribute to the pathology of some epilepsy syndromes. A sensitive monoclonal antibody against GluR3-subtype of AMPA/glutamate receptor (GluR3B). Applications: Suitable for use in Flow Cytometry, ELISA, Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 5ug/ml ELISA: 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice