Enkephalin (Endorphins, Endorphin, Met5-Enkephalin, Leu5-Enkephalin, Met-Enkephalin, Leu-Enkephalin)

Size

£607.00

SKU:: 301632
Purity:: Supernatant
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Pentapeptide (Tyr-Gly-Gly-Phe-Leu)
Clone:: NOC1
Format:: Supplied as a lyophilized powder in 0.05% thimerosal. Reconstitute with 500ul ddH2O.
Extra Details:: Enkephalins (penta-peptides) have been discovered as regulators of nerve impulses involving pain in the brain. It has been shown that these peptides act as natural analgesics (pain-killers) and their action mimics that of morphine and other opiates. At present, it is thought that the morphine-like effects are due to aromatic side chains on phenylanine and tyrosine which mimic a similar structure on morphine. Research suggests that it does not make much difference whether the enkephalin contains methionine or leucine at the acid end of the peptide for its action. A specific and sensitive antibody against enkephalinergic fibrilar networks in the globus pallidus, N. accumbens, septum, hypothalamus, thalamus, amygdala, N. interstitialis of the stria terminalis and brain stem nuclei Applications: Suitable for use in RIA, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 1:100-1:400 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice