Neprilysin (NEP, Neutral Endopeptidase, CD10) (PE)

Size

£837.00

SKU:: 301413-PE
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to the internal sequence of human Neprilysin.
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Extra Details:: Neprilysin (NEP) is a functional neutral endopeptidase of the type that has previously been called enkephalinase or atriopeptidase. NEP mRNA levels are significantly decreased in both Alzheimer’s disease and amyloid plaques individuals. This decreased MME expression correlates with amyloid-beta deposition but not with degeneration and dementia. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Immunohistochemistry: 1:100-1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.