Skip to content
  1. Shop all

301331-HRP

CLAC-P, NC2-2 Region (CLAC-P NC2-2, Collagen-like Alzheimer Amyloid Plaque Component, CLACP) (HRP)

Size

£837.00

SKU:
301331-HRP
Application:
WB
Purity:
Purified by immunoaffinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Residues aa155-169 [KGEQGDQGPRMVFPK] at the NC2-2 region of human CLAC-P.
Format:
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Extra Details:
The 9D2 antigen isolated from senile plaque amyloid was identified as collagen-like Alzheimer amyloid plaque component (CLAC), and its precursor as CLACP/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bind to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice