Antiplasmin, alpha 2, Human (A2AP, Alpha-2-Antiplasmin, Alpha-2 Antiplasmin)

Size

£466.00

SKU:: 301310
Molecular Weight:: 6370
Purity:: ≥95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in 20mM Bis-Tris, pH 6.4, 200mM sodium chloride. No preservative added. Reconstitute using neutral pH buffer of choice, avoiding extreme high and low pH.
Extra Details:: Alpha-2 Antiplasmin (A2AP) is a serine protease inhibitor (serpin) responsible for inactivating plasmin, an important enzyme that participates in fibrinolysis and degradation of various other proteins. In liver cirrhosis, there is decreased production of alpha-2 antiplasmin, leading to lowered inactivation of plasmin and an increase in fibrinolysis. This is associated with an increase risk of bleeding in liver disease. Synonyms: A2AP, Alpha-2-Antiplasmin, Alpha-2 Antiplasmin Molecular Weight: ~63-70kD Specific Activity: ≥ 5IU/mg protein Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.