Sodium Aescinate

Size

£230.00

SKU:: 300986
Molecular Weight:: 1124.23
Purity:: ≥90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 20977-05-3
Format:: White to off-white powder
Extra Details:: Sodium aescinate is used as a vasoactive drug in clinical treatment. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway. Sodium aescinate can block signals transiting to downstream molecules AKT, ERK, inhibit the proliferation of breast cancer cell MCF-7 cell apoptosis and induced cell apoptosis by suppressing the activation of SRC[3]. Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[1]. Sodium aescinate treatment can alleviate the symptom of polycystic ovary syndrome (PCOS) in rat model through regulating the PI3K/Akt/GSK3-β pathway[4]. Synonyms: Escin monosodium salt Botanical Source: Aesculi semen CAS Number: 20977-05-3 Molecular Formula: C55H86NaO23 Molecular Weight: 1124.23 Appearance: White to off-white powder Purity (HPLC-DAD or/and HPLC-ELSD): ≥90% Identification Method: Mass, NMR Solubility: DMSO (10mg/ml) Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.