Schisanwilsonin I

Size

£554.00

SKU:: 300932
Molecular Weight:: 514.57
Purity:: ≥98%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1181216-84-1
Format:: White to off-white solid
Extra Details:: Seven new dibenzocyclooctane lignans, schisanwilsonins A–G (1–7), were isolated from the fruits of Schisandra wilsoniana, together with five known lignans (8–12). The structures of these new compounds were elucidated by spectroscopic methods including 2D-NMR techniques. The 12 lignans were tested for anti-hepatitis B virus (HBV) activity in vitro. Schisanwilsonin D (4), schisantherin C (9), deoxyschizandrin (10) and (+)-gomisin K3 (11) showed anti-HBV activity. 9 exhibited the most potent anti-HBV activity with potency against HBsAg and HBeAg secretion by 59.7% and 34.7%, respectively, at 50ug/ml. Source: Fruits of Schisandra wilsoniana Synonyms: [(8S,9R,10S)-9-hydroxy-3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-8-yl] (E)-2-methylbut-2-enoate CAS Number: 1181216-84-1 Molecular Formula: C28H34O9 Molecular Weight: 514.57 Appearance: White to off-white solid Purity: ≥98% Analysis Method: HPLC-DAD or/and HPLC-ELSD Identification Method: Mass, NMR Solubility: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.