FOX1 (Fox-1 Homolog A, A2BP1, A2BP, Ataxin-2-Binding Protein 1, HRNBP1, Hexaribonucleotide-Binding Protein 1, RBFOX1, RNA Binding Protein Fox-1 Homolog 1)

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£633.00

SKU:: 299381
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa1-100 of human FOX1 at N-terminal, expressed in E. coli.
Clone:: 15H207
Format:: Supplied as a liquid in PBS, 10mM sodium azide.
Extra Details:: Fox1 is one of a family of 3 mammalian Fox1 homologues. Fox was discovered in C. elegans as a gene involved in sex determination, and the name Fox is an acronym of "Feminizing locus on X". The Fox protein and its 3 mammalian homologues are all about 46kD proteins each of which includes a central highly conserved RRM type RNA recognition motif, which corresponds to a small ~70aa structure consisting of 4 beta strands and two alpha-helices. An alternate name for Fox 1 is ataxin-2 binding protein 1 (A2BP1). Like Fox3, Fox1 is expressed in neuronal nuclei, but with a different pattern of expression than Fox3. For example, in the cerebellum Fox3 does not stain Purkinje neurons and Golgi neurons, but these two neuron types are stained by Fox1 antibody. Applications: Suitable for use in Immunofluorescence, Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:1:500-1:1000 Western Blot: 1:1000-1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice