CD105, Recombinant, Human, aa26-176 (Endoglin, GP160)

Size

£550.00

SKU:: 299331
Molecular Weight:: 43
Purity:: ≥90% (RP-HPLC, SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA, 20% glycerol.
Extra Details:: CD105 (aa26-176), Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGFBeta1 and Beta3 with high affinity but not TGF-Beta2. Recombinant protein corresponding to aa26-176 of human CD105, expressed in E. coli. Molecular Weight: ~43kD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.