299284
5-Hydroxytryptophan (5-HTP, 5HTP, Oxitriptan, INN) (Not for Export EU)
Size
£572.00
- SKU:
- 299284
- Application:
- IHC-Fr
- Purity:
- Serum
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- 5-HTP, coupled to BSA with paraformaldehyde.
- Format:
- Supplied as a lyophilized powder in 0.09% sodium azide. Reconstitute with 100ul sterile ddH2O.
- Extra Details:
- 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor as well as metabolic intermediate in the biosynthesis of the neurotransmitters serotonin and melatonin from tryptophan. 5-Hydroxytryptophan is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT) by the enzyme aromatic-L-amino-acid decarboxylase with the help of vitamin B6. This reaction occurs both in nervous tissue and in the liver. 5-HTP crosses the blood-brain barrier, while 5-HT does not. Since 5-HTP incresease levels of serotonin, it is used to treat depression, sleep disorders and pain. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (biotin-avidin/HRP staining): 1:1000-1:2000 in PBS, 0.3% Triton X-100 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice