299110
CD39L3 (Ectonucleoside Triphosphate Diphosphohydrolase-3, ENTPD3)
Size
£761.00
- SKU:
- 299110
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography from culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to mouse CD39L3.
- Clone:
- 15H21(RM0391-16O3)
- Format:
- Supplied as a lyophilized powder in PBS. Reconstitute with 500ul sterile PBS.
- Extra Details:
- Ectonucleoside triphosphate diphosphohydrolase-3 (NTPDase-3) is an integral membrane protein with an extracellular catalytic domain. rhNTPDase-3 was expressed as a protein lacking its N- and C-terminal transmembrane domains, resulting in the secretion of the soluble rhNTPDase-3 ectodomain. NTPDase-3 hydrolyzes the beta-and gamma -phosphate groups of nucleotides, preferring ATP, ADP, UTP, and UDP as substrates. Through its hydrolysis of extracellular nuceotides, NTPDase-3 is important for the regulation of purinergic signaling. The enzyme is expressed at its highest levels in brain, pancreas, spleen, and prostate tissues. In the brain, NTPDase-3 may play a role in the regulation of feeding, sleep, and other behaviors. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Mouse myeloma cells with spleen cells from rat. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice