298190
L-Kynurenic Acid (KynA, 4-Hydroxyquinoline-2-Carboxylic Acid, Kinurenic Acid, Kynuronic Acid, Quinurenic Acid, Transtorine) (Not for Export EU)
Size
£403.00
- SKU:
- 298190
- Purity:
- Serum
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- L-Kynurenic Acid
- Format:
- Supplied as a lyophilized powder. Reconstitute with sterile ddH2O.
- Extra Details:
- Kynurenic acid is a product of the normal metabolism of amino acid L-tryptophan. It is formed from L-kynurenine, a reaction catalyzed by the enzyme kynurenine-oxoglutarate transaminase. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important neurophysiologic and neuropathologic processes. As a result, kynurenic acid has been considered for use in therapy in certain neurobiological disorders. High levels of kynurenic acid have been identified in human urine in certain metabolic disorders, such as marked pyridoxine deficiency and deficiency/absence of kynureninase. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice