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298113

ADMA (Asymmetric Dimethylarginine) (Not for Export EU)

Size

£422.00

SKU:
298113
Purity:
Serum
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Asymmetric Dimethylarginine, KLH conjugated
Format:
Supplied as a lyophilized powder. Reconstitute with sterile ddH2O.
Extra Details:
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardiovascular health. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:100 Optimal dilutions to be determined by the researcher. Crossreactivity: Using conjugated ADMA-KLH, antibody specificity was performed with an ELISA test by competition experiments with the following compounds: Compound: Cross-reactivity ratio(a): ADMA-BSA: 1 SDMA-BSA: 1/>100 NDMA-BSA: 1/>100 L-Arginine-BSA: 1/>5000 (a) ADMA-BSA concentration/unconjugated or conjugated amino acids concentration at half displacement BSA = Bovine Serum Albumin Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice