Dioscin

Size

£384.00

SKU:: 296932
Molecular Weight:: 869.04
Purity:: ≥98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 19057-60-4
Format:: White to off-white powder
Extra Details:: Dioscin is a natural compound that has been shown to have cytotoxic effects on human tumor cells. Dioscin has been found to be an apoptosis-inducing factor, which activates the mitochondrial pathway of apoptosis. It has also been shown to inhibit the proliferation of 3T3-L1 preadipocytes and HL-60 cells by affecting the bcl-2 protein and toll-like receptor pathways. Dioscin is effective in treating myocardial infarcts, as well as other injuries such as squamous cell carcinoma. Synonyms: (+)-Dioscin; 3-O-β-D-α-L-Rhamnopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranoside-diosgenin; Collettiside III; Dioscine; Diosgenin 3-O-α-L-Rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside; Diosgenin 3-O-α-L-Rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside; Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside; Paris III; Polyphyllin III; (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside CAS No: 19057-60-4 Molecular Formula: C₄₅H₇₂O₁₆ Molecular Weight: 869.04 Appearance: White to off-white powder Purity: ≥98% (HPLC) Loss on Drying: ≤5% Sulfated Ash: ≤1% Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

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