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296176

Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt

Size

£428.00

SKU:
296176
Molecular Weight:
521.21
Purity:
≥95%
Storage Conditions:
4°C
Supplier:
United States Biological
CAS Number:
13912-93-1
Format:
White to off-white powder
Extra Details:
Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt (GMPP) is an analog of guanosine triphosphate that is enzymatically inactivated by the enzyme kinesin. GMPP inhibits the polymerization of microtubules by binding to the kinesin molecule and preventing it from binding to tubulin. GMPP has been shown to inhibit sephadex g-100 chromatography and act as a competitive inhibitor for protein synthesis in vitro. GMPP has also been shown to have a fat cell differentiation effect which may be due to its ability to inhibit microtubule polymerization. Synonyms: GMPPCP; GppCp CAS No: 13912-93-1 Molecular Formula: C11H18N5O13P3·xNa Molecular Weight: 521.21 Appearance: White to off-white powder Purity: ≥95% 1H-NMR Spectrum: Conforms to reference Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Ambient