7-Deazaguanosine

Size

£329.00

SKU:: 295746
Molecular Weight:: 282.25
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 62160-23-0
Extra Details:: 7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses. Synonyms: 2-Amino-7-(ß-D-ribofuranosyl[3,2-d]pyrimidin-4-one; 2-Amino-1,7-dihydro-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one CAS No: 62160-23-0 Molecular Formula: C11H14N4O5 Molecular Weight: 282.25 Purity: ≥98% (TLC) Appearance: White to off-white powder Identity (1H NMR): Conforms to reference Melting Point: >250°C dec (lit) Storage and Stability: Store at 4ºC. Product is stable for 12 months after receipt.