Tizoxanide-D-glucuronide Sodium Salt

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£576.00

SKU:: 294886
Molecular Weight:: 463.35
Purity:: ≥95% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 221287-83-8
Format:: Yellow solid
Extra Details:: Tizoxanide Glucuronide, Sodium Salt is a metabolite of nitazoxanide and acts as a substrate for the enzyme uridine diphosphate-glucuronosyltransferase. This enzyme catalyzes the transfer of glucuronic acid from uridine diphosphate to the drug tizoxanide, resulting in the formation of tizoxanide glucuronide. The tizoxanide glucuronide is then further metabolized by other enzymes, resulting in the formation of tizoxanide glucuronide, sodium salt. Synonyms: Sodium (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-((5-nitrothiazol-2-yl)carbamoyl)phenoxy)tetrahydro-2H-pyran-2-carboxylate; 2-[[(5-Nitro-2-thiazolyl)amino]carbonyl]phenyl β-D-Glucopyranosiduronic Acid Monosodium Salt, Tizoxanide O-b-D-glucuronide sodium CAS No: 221287-83-8 Molecular Formula: C16H14N3NaO10S Molecular Weight: 463.35 Appearance: Yellow solid Purity: ≥95% (HPLC) NMR, MS: Conforms to reference Specific Rotation: -26.0° (c = 0.1, Water; 5 Hours) Solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) Storage and Stability: Store at 4°C under inert atmosphere. Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.