Indomethacin acyl-b-D-glucuronide

Size

£559.00

SKU:: 293760
Molecular Weight:: 533.91
Purity:: ≥96%
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 75523-11-4
Format:: Off-white to green solid
Extra Details:: Indomethacin Indomethacin acyl-b-D-glucuronide is a prodrug of indomethacin. It is absorbed through the stomach and small intestine and metabolized in the liver. The pharmacokinetic parameters are not as well understood as with other drugs, but it has been shown that indomethacin acyl-b-D-glucuronide has a higher systemic exposure than indomethacin. This may be due to an increase in absorption or faster elimination. Indomethacin acyl-b-D-glucuronide is used for the treatment of pain and inflammation associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gouty arthritis, and bursitis. Synonyms: 1-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate] ?-D-Glucopyranuronic Acid; Indomethacin Glucuronide CAS No: 75523-11-4 Molecular Formula: C₂₅H₂₄ClNO₁₀ Molecular Weight: 533.91 Appearance: Off-white to green solid Purity: ≥96% Melting Point: 80-87°C Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.