3,4-Dideoxyglucosone-3-ene

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£633.00

SKU:: 293249
Molecular Weight:: 144.13
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 252006-38-5
Extra Details:: Bioreactive glucose degradation product which can be formed during heat sterilisation of glucose containing peritoneal dialysis solutions. Chemically, 3,4-Dideoxyglucosone-3-ene is an unsaturated carbonyl compound which increases its reactivity with cellular sulfhydryl, amino groups, proteins, and DNA. 3,4-Dideoxyglucosone-3-ene induces apoptosis in neutrophils, renal cells and peripheral blood mononuclear cells. Such induction leads to impaired peritoneal antibacterial defense. Synonyms: 3,4-DGE; (6R)-2-Hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one; (6R)-2-Hydroxy-6-(hydroxymethyl)-2,6-dihydropyran-3-one CAS No: 252006-38-5 Molecular Formula: C6H8O4 Molecular Weight: 144.13 Purity: ≥98% (HPLC) Appearance: Light yellow oil Storage and Stability: Store at -20°C. Stable for 6 months after receipt