Tauroursodeoxycholic Acid (TUDCA)

Size

£409.00

SKU:: 289698
Molecular Weight:: 499.71
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 14605-22-2
Extra Details:: Tauroursodeoxycholic acid (TUDCA) is a bile acid that is naturally present in the body. It has been found to protect against cell membrane injury and to improve recovery from kidney injury. TUDCA also inhibits the production of proinflammatory cytokines, such as IL-6 and TNF-α, by binding to the protein bcl-2. This prevents apoptosis and promotes cell survival. In addition, TUDCA has been shown to have antioxidant properties that may be due to its ability to bind with reactive oxygen species (ROS). The anti-inflammatory effects of TUDCA are thought to be mediated by its ability to decrease the production of ROS and inhibit NF-κB activation. Synonyms: 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid; 3α,7β-dihydroxy-5β-cholanoyl Taurine; TUDCA; UR-906; Ursodoxicoltaurine CAS No: 14605-22-2 Molecular Formula: C26H45NO6S Molecular Weight: 499.71 Purity: ≥98% Appearance: White to off-white powder Melting Point: >140°C (dec.) (lit) Method of Determining Identity: Proton NMR Spectrometric Analysis Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Stable for 6 months after receipt. Hygroscopic.