Sofosbuvir (PSI-7977, GS-7977)

Size

£351.00

SKU:: 289451
Molecular Weight:: 529.45
Purity:: ≥99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 1190307-88-0
Format:: White to yellow powder
Extra Details:: PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: Isopropyl(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-1-methylethyl Ester L-Alanine; GS-7977; PSI-7977 CAS Number: 1190307-88-0 Molecular Formula: C22H29FN3O9P Molecular Weight: 529.45 Appearance: White to yellow powder Purity: ≥99% (HPLC) Identity (1H NMR): Conforms to structure Water (KF): ≤1% Storage and Stability: Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.