Regorafenib

Size

£223.00

SKU:: 288607
Molecular Weight:: 482.82
Purity:: ≥99% (HPLC, TLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 755037-03-7
Format:: Supplied as a white to off-white powder.
Extra Details:: Inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N’-(4-Chloro-3-trifluoromethylphenyl)ureido]-3- fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; BAY 73-4506; Fluoro-Sorafenib; Stivarga CAS Number: 755037-03-7 Molecular Formula: C₂₁H₁₅ClF₄N₄O₃ Molecular Weight: 482.82 Appearance: Supplied as a white to off-white powder. Purity: ≥99% (HPLC, TLC) Melting Point: 185-186ºC Solubility: DMSO Elemental Analysis: Calculated: %C: 52.24 %H: 3.13 %Cl: 7.34 %F: 15.74 %N: 11.60 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.