Proxylphylline

Size

£205.00

SKU:: 287649
Molecular Weight:: 238.24
Purity:: ≥99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 603-00-9
Format:: White to off-white powder
Extra Details:: Proxylphylline is a methylxanthine drug that is used to treat bronchial asthma. It is an anti-inflammatory agent that acts by inhibiting phosphodiesterases, which are enzymes that break down cyclic nucleotides such as cAMP and cGMP. Proxylphylline has been shown to have inotropic effects on the heart, increasing the force of contraction and decreasing the time between contractions. This drug also reverses the bronchoconstricting effects of allergens. Proxylphylline is absorbed into cells through a chloride channel and then converted to theophylline before it inhibits phosphodiesterases. Theophylline is metabolized in the liver to 3-methylxanthine, 1-methyluric acid, and 1-methylurate. Synonyms: 7-(2-Hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 7-(2-Hydroxypropyl)-1,3-dimethylxanthine; Monophylline; Spasmolysin CAS No: 603-00-9 Molecular Formula: C10H14N4O3 Molecular Weight: 238.24 Appearance: White to off-white powder Purity (HPLC): ≥99% Melting Point: 134-138°C Solubility: 134-138°C Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.