Paroxetine Hydrochloride

Size

£293.00

SKU:: 287528
Molecular Weight:: 365.83
Purity:: As reported
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 78246-49-8
Format:: White to off-white solid
Extra Details:: Paroxetine is a phenylpiperidine derivative that potently and selectively inhibits the reuptake of serotonin, blocking the human serotonin transporter with a Ki value of 0.72nM.1 It less effectively blocks the human norepinephrine and dopamine transporters (Ki = 440 and 1,900nM, respectively).1 Paroxetine also inhibits, at concentrations in excess of 1uM, nitric oxide synthase activity in the cytosol of hamster brain.2 Selective serotonin uptake inhibitors, including paroxetine, are used in cases of depression and anxiety disorder.3,4 Synonyms: (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride; Aropax; Deroxat; Paxil; Seroxat CAS No: 78246-49-8 Free base: 61869-08-7 Molecular Formula: C19H20FNO3·HCl Molecular Weight: 365.83 Appearance: White to off-white solid Purity: As reported Melting Point: 136-142°C Solubility: Methanol (Slightly), Water (Slightly, Heated) Storage: 4°C