PLX4032 (Vemurafenib)

Size

£626.00

SKU:: 287416
Molecular Weight:: 489.92
Purity:: ≥99% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 918504-65-1
Format:: Supplied as a white to off-white powder
Extra Details:: Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Identity (1H NMR): Conforms to structure Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: As of September 2011 the current correct CAS number for vemurafenib, also known as PLX4032, is given above. Chemical Abstracts Service recently canceled another CAS number, 1029872-54-5, that had previously been used for vemurafenib under its older name, PLX4032. However, this canceled number remains in wide use and receives the vast majority of hits on Google.