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281320

Leupeptin Trifluoroacetate

Size

£351.00

SKU:
281320
Molecular Weight:
540.59
Purity:
≥90% (HPLC)
Storage Conditions:
4°C
Supplier:
United States Biological
CAS Number:
147385-61-3
Format:
White to off-white powder
Extra Details:
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.) Synonyms: Acetyl-Leu-Leu-Arg-al trifluoroacetate salt; Leupeptin TFA CAS No: 147385-61-3 Molecular Formula: C₂₂H₃₉F₃N₆O₆ Molecular Weight: 540.59 Appearance: White to off-white powder Purity: ≥90% (HPLC) Melting Point: NA Solubility: Water: 10mM (Solutions are stable only a few hours. Stock solutions are stable up to 6 months at -20°C.) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Ambient