Ketoconazole

Size

£160.00

SKU:: 281105
Molecular Weight:: 531.43
Purity:: ≥98%
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 65277-42-1
Format:: White to light brown powder
Extra Details:: Ketoconazole is an inhibitor of cytochrome P450c17. Enhances the formation of myelin basic protein-positive oligodendrocytes from oligodendrocyte progenitor cells in vitro and promotes remyelination in vivo. Also an antifungal agent. Brain penetrant. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Inhibitor of exosome secretion. Synonyms: rel-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]ethanone; cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; (+/-)-Ketoconazole CAS No: 65277-42-1 Molecular Formula: C26H28Cl2N4O4 Molecular Weight: 531.43 Purity: ≥98% Appearance: White to light brown powder Melting Point: 148-152ºC Loss on Drying (80°C, 4hr): ≤0.5% Solubility: Ethanol, DMSO, Chloroform (Slightly), Methanol (Slightly) Storage and Stability: Store at 4ºC. Stable for 6 months after receipt.