Imiquimod

Size

£287.00

SKU:: 280414
Molecular Weight:: 240.3
Purity:: ≥98%
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 99011-02-6
Format:: White crystalline powder
Extra Details:: Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway. Stimulates proinflammatory cytokine production interferon-alpha (IFN-alpha), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and activates NF-kappaB. Caspase-3 activator that directly induces procaspase-3 cleavage. Anti-cancer compound. Apoptosis inducer. Antiproliferative, independent of immune system activation or function. Approved treatment for external genital warts caused by human papillomavirus infection. Synonyms: 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline; S26308; R-837 CAS Number: 99011-02-6 Molecular Weight: 240.30 Molecular Formula: C14H16N4 Appearance: Supplied as a white to off-white powder. Purity: ≥98% Solubility: DMSO or dimethylformamide. Insoluble in ethanol. Slightly soluble in water. Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.