GW 501516

Size

£576.00

SKU:: 278374
Molecular Weight:: 453.5
Purity:: ≥98%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 317318-70-0
Format:: White to yellow powder
Extra Details:: An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. Synonyms: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid; Methyl-methyl-trifluoromethylphenyl_x000B_-thiazolyl-methylsulfanyl-phenoxy-acetic Acid; GW 1516; Endurobol CAS No: 317318-70-0 Molecular Formula: C₂₁H₁₈F₃NO₃S₂ Molecular Weight: 453.5 Appearance: White to yellow powder Purity: ≥98% Melting Point: 134-144°C Solubility: DMSO (Slightly), Methanol (Slightly) Water: ≤0.5% Storage and Stability: May be stored at 4°C for short-term. For long-term storage, aliquot and store at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.