6,8-Difluoro-7-hydroxy-4-methylcoumarin

Size

£293.00

SKU:: 272967
Molecular Weight:: 212.15
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 215868-23-8
Extra Details:: Synthetic coumarin derivative that has been shown to inhibit the activity of phosphatases. This compound binds reversibly to phosphatases and can be used in diagnostic tests. 6,8-DFMC has been shown to bind specifically to recombinant proteins containing a consensus sequence for phosphatase binding sites. The binding affinity of this compound is higher than those of other coumarins. 6,8-DFMCl also inhibits the production of TNFα by human cells and has been shown to be effective against both tumor and non-tumor cells. This drug is structurally related to 4-methylumbelliferone (4MU), which has been shown to have anticancer effects. Synonyms: DiFMU; Marina blue; 6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one CAS No: 215868-23-8 Molecular Formula: C10H6F2O3 Molecular Weight: 212.15 Purity: ≥95% Appearance: White to off-white solid Emission: 455nm Solubility: DMSO, DMF, Methanol Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.