Crospovidone (PVP)

Size

£442.00

SKU:: 269236
Molecular Weight:: 0
Storage Conditions:: RT
Supplier:: United States Biological
CAS Number:: 25249-54-1, 9003-39-8
Extra Details:: Crospovidone is a polymer that is used in the production of tablets and capsules. It is a water-soluble polyvinylpyrrolidone, which is obtained by the condensation of vinyl acetate with pyrrolidine. Crospovidone has been shown to have toxicological properties in vitro, but not in vivo. In vitro studies have demonstrated that crospovidone has no effect on cell lysis or human serum. It also does not inhibit dapagliflozin, an inhibitor of sodium glucose cotransporter 2 (SGLT2), which is a therapeutic target for type 2 diabetes mellitus. Crospovidone has been shown to be effective as a tablet binder in combination with other polymers such as carbopol and hydroxypropyl cellulose (HPC). Synonyms: Polyvinyl polypyrrolidone; crospolividone; Polyvinylpyrrolidone cross-linked CAS No: 9003-39-8, 25249-54-1 Molecular Formula: (C₆H₉NO)n Particle Size (5-50um): ≥80% Appearance: White to off-white to yellowish powder Melting Point: ~165°C (dec.)(lit.) pH: 5-7 Nitrogen: 11-13% Heavy Metals: ≤0.001% Water (KF): ≤5% Peroxide (as H2O2): ≤0.04% Sulfated Ash: ≤0.1% Soluble Components: ≤1.5% Monomers: ≤0.1% Storage and Stability: Store at RT. Stable for 12 months after receipt.