4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside (GlcNAc1-b-4MU)

Size

£288.00

SKU:: 257717
Molecular Weight:: 379.36
Purity:: ≥98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 37067-30-4
Format:: White to off-white powder
Extra Details:: Fluorogenic substrate used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms. Synonyms: 4-Methylumbelliferyl N-acetyl-b-D-glucosaminide; 4-MU-GlcNAc; M3C; GlcNAc-b-4MU CAS No: 37067-30-4 Molecular Formula: C₁₈H₂₁NO₈ Molecular Weight: 379.36 Appearance: White to off-white powder Purity: ≥98% (HPLC) Identity (FT-IR): Conforms to structure Melting Point: 212-214°C Specific Optical Rotation [α]D20 (c=1, pyridine): -28 to -32° _x000B_Fluorescence: max. Abs. l = 325nm, max. Em. l = 378nm Free 4-MU: ≤0.01% Water (Karl Fischer): ≤1% Solubility: Methanol, Warm Water , DMF Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.