Amikacin Anhydrous

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£403.00

SKU:: 257213
Molecular Weight:: 585.6
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 37517-28-5
Extra Details:: Amikacin hydrate is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin hydrate is freely soluble in aqueous solution. Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited. Samples of microbes grown in the presence of a 30 μg amikacin disc with a zone of inhibition of <14 mm in diameter are considered resistant. Intermediate resistance zones of inhibition are typically 15 mm-16 mm in diameter. Synonyms: D-Streptamine; (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide; O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-; (S)-, O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D-streptamine; 1-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A; Amicacin; Amigasol; Amikacillin; Amikacin; Amikozit; Amukin; Antibiotic BB-K 8; Arikace; BAY 41-6551; Lukadin; Potentox CAS No: 37517-28-5 Molecular Formula: C₂₂H₄₃N₅O₁₃ Molecular Weight: 585.60 Purity: ≥98% Appearance: White to off-white powder Solubility: PBS (pH 7.2): 5mg/ml Melting Point: 214-215°C (lit) NMR: Conforms to structure Method for Determining Identity: Mass Spectometry Storage and Stability: May be stored at -20°C. Stable for 6 months after receipt at -20°C.

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